A simple blood test developed by BC Cancer Agency and Vancouver Prostate Centre researchers may help determine treatment for prostate cancer in the near future

Date Posted: 
2014-08-13

A new blood test developed by researchers at the BC Cancer Agency and the Vancouver Prostate Centre is garnering international attention, and has the potential to improve the way a deadly form of prostate cancer, metastatic castration-resistant prostate cancer (CRPC), is treated.

Medical oncologist Dr. Kim Chi and his team have been able to detect prostate cancer DNA (genetic code circulating in the blood) in most patients with CRPC. When the DNA is analyzed it can provide information on the genetic programming of a particular person’s prostate cancer, which can help guide treatment decisions. Previously, the only way to genetically profile a person’s metastatic cancer was through a biopsy, which can be painful, difficult and have complications.

Knowing which type of prostate cancer a patient has can dictate which drug therapies will be most effective and which will be least effective, allowing doctors to be more precise with their treatment recommendations. In a recent study Dr. Chi and his colleagues evaluated whether the genetic profile of men’s prostate cancer would be responsive or not to the latest hormone therapies. They identified key irregularities, androgen receptor (hormone) amplification and the F876L AR mutation, as determining factors in whether prostate cancer responds to hormone therapy.  The blood test can potentially be used during treatment as well, to analyze changes over time and allow for an ongoing “personalized medicine” approach.

The results of Dr. Chi’s most recent study was presented at the American Society of Clinical Oncology (ASCO) international general meeting.

A World Class Centre

The Vancouver Prostate Centre (VPC) has a track record of success that has earned it a reputation as one of the world’s most respected cancer facilities. It is a National Centre of Excellence and a designated Centre of Excellence for Commercialization and Research.

Events

VPC Terry Fox team 2016

Terry Fox Run: Sunday September 16, 2018

On Sunday September 16, the fundraising Terry Fox walk/run/ride is taking place across Canada.  We are grateful for our  grant support provided by The Terry Fox Foundation and Terry Fox Research Institute continously since 1998 - click here to donate to our team (opens in new window)

 

Vancouver

18th Annual Pacific Northwest Prostate Cancer Conference: Sat Sept 22, 2018

The 18th Annual Pacific Northwest Prostate Cancer Conference for patients, their families and health care professionals will be held in Vancouver on Saturday September 22, from 8 AM to 4 PM.  Click here for further details and to purchase tickets ($30, includes lunch). (Opens in new window)

 

Employment

Work at the Vancouver Prostate Centre

Thursday, July 26, 2018

Dr. Gleave awarded the 2018 Dr. Chew Wei Memorial Prize in Cancer Research

Dr. Gleave
Tuesday, May 29, 2018

Three VPC trainees receive 2018 VCHRI Rising Star Awards

2018 Rising Star Awardees
DNA

Make A Difference

Help the Vancouver Prostate Centre fund research to find better treatments and a cure.