Dr. Xuesen Dong

Dr. Xuesen Dong

M.Sc. Laval Université 2000
Ph.D. University of Toronto 2005

Clinical and Research Scientists

Senior Research Scientist, Vancouver Prostate Centre
Associate Professor, Department of Urologic Sciences, University of British Columbia


Dr. Dong received medical school training from China before coming to Canada. He completed an MSc in Molecular and Cellular Biology at Laval University and a PhD in Physiology at the University of Toronto. He received post-doctoral training from the Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto and the Vancouver Prostate Centre, University of British Columbia. He was a recipient of several scholarships for his doctoral and post-doctoral training. He was awarded as a Rising Star by Prostate Cancer Canada.

Dr. Dong’s laboratory investigates steroid receptors in collaborating with RNA splicing factors to control gene transcription and alternative RNA splicing in cells from human reproductive systems. We study how prostate cancer cells can switch off their dependency to androgens and progress into castration resistant cancers. We also study how myometrial cells can develop a functional withdrawal of progesterone at late pregnancy to change the myometrium from a dormant state to the contractile state for parturition.

Dr. Dong enjoys inspiring young investigators to practise biomedical research. Our lab always welcomes ambitious and self-driven young scientists who have strong passion for research to join us.

A World Class Centre

The Vancouver Prostate Centre (VPC) has a track record of success that has earned it a reputation as one of the world’s most respected cancer facilities. It is a National Centre of Excellence and a designated Centre of Excellence for Commercialization and Research.


2016 Step Up team

Step Up Challenge fundraiser: February 25, 2018

The annual Step Up Challenge, raising funds for Prostate Cancer Canada, takes place in Vancouver on Sunday February 25. Click here to sponsor our relay team as they climbs 379 floors. Click here to volunteer to help with the event.

It's a Snow Day poster

It's A Snow Day at Mt. Seymour: March 9

Mt. Seymour is hosting It's A Snow Day, a fundraiser for Prostate Cancer Foundation BC, on Friday March 9. The event will include slope time, a reception, and a silent auction. Click here for more details including how to register, donate and/or sponsor.




Work at the Vancouver Prostate Centre

Thursday, January 18, 2018

Discovery of a promising new medication to block "master key" of cancer growth

Dr. Chris Ong
Tuesday, February 20, 2018

Drs. Wyatt and Chi: ctDNA predicts resistance to AR-targeted therapy

VCHRI News article on study of ctDNA predicting resistance to AR-targeted therapy

Make A Difference

Help the Vancouver Prostate Centre fund research to find better treatments and a cure.