Critical funding from our research partners and donors has helped us to attract and retain the very best research talent from around the world, which in turn, increases our ability to move discoveries further along into clinical research and eventually treatments.
PhD Student (2), Daugaard Lab
The Vancouver Prostate Centre (VPC) has an exceptional opportunity available for 2 PhD Students to join our research team.
The Vancouver Prostate Centre
The VPC has a large number of multi-disciplinary research programs in basic, clinic, and translational cancer research. It is a National Centre of Excellence and a designated Centre of Excellence for Commercialization and Research. It is affiliated with the University of British Columbia and the Vancouver Coastal Health Authority.
The Daugaard laboratory focuses on innovative research in molecular cancer biology developing biotechnology for diagnostic and therapeutic use in different cancer indications. The successful applicant will work in a multi-disciplinary research team with access to state-of-the-art equipment and facilities in collaboration with national and international research groups and pharmaceutical companies.
Project 1: Ewing sarcoma (EWS) is the second most common bone cancer in children and adolescents with a high metastatic potential. EWS development is driven by specific chromosomal translocations resulting in generation of chimeric EWS-ETS transcription factors. In this project, the student will develop different screening approaches to select compounds to target EWS-FLI1 activity with high specificity. The student will perform in vitro and in vivo experiments and will work in collaboration with chemists, biologists, bioinformaticians and clinicians.
Project 2: The dysregulation of the 3’UTR landscape is a fundamental signature of many types of cancer. In this CIHR funded project, the successful applicant will have to interrogate the mechanisms underlying alternative poly-adenylation (APA) of 3’UTRs of oncogene-induced mRNAs and assess the impact hereof on tumor initiation and progression. The project is part of a collaboration with SickKids Hospital in Toronto, ON.
Click here for more information on Dr. Daugaard and his team.
Qualifications and Requirements
- Bachelor’s or Master’s degree in Biochemistry, Molecular Biology, or similar.
- Demonstrated experience in RNA molecular biology.
- Strong problem-solving skills.
- Statistical data analysis and database management skills.
- Excellent written and verbal communication skills.
- Friendly, organized, and detail-oriented team player.
To apply for this position, please email careersprostatecentre [dot] com with subject line PhD Student, Daugaard Lab with the following items attached:
- Cover letter that includes a motivation statement and a qualification statement
- Current CV
- University transcript
NOTE: Applications will be accepted until November 10, 2018. Please be prepared to provide the names and contact information of 3 references if successfully selected.
No telephone calls or drop-in inquiries accepted. Only those under consideration will be contacted.