Dr. Syam Somasekharan

Dr. Somasekharan

PhD, Department of Biochemistry, Indian Institute of Science (2001-2006)
Post-Doctoral Fellow, Department of Cell Biology, Faculty of Science, University of Geneva (2007-2010)
Post-Doctoral Fellow, Department of Pathology, Faculty of Medicine, University of British Columbia (2010-2015)
Ramanujan Fellow, Department of Biosciences and Biomedical Engineering, Indian Institute of Technology (2015-2016)


Clinical and Research Scientists

Senior Research Scientist, Vancouver Prostate Centre
Assistant Professor, Department of Urologic Sciences, University of British Columbia


Dr. Syam Somasekharan joined the Vancouver Prostate Centre as a Research Scientist in 2016, and was appointed Senior Research Scientist in 2021.

Graduating with a Ph.D. in Biochemistry at the Indian Institute of Science, Dr. Somasekharan proceeded to do his post-doctoral fellowships at the Department of Cell Biology, University of Geneva and the Department of Pathology, University of British Columbia, investigating the molecular mechanisms of apoptosis and mRNA translation. After his post-doctoral research, Dr. Somasekharan received the Early Career Research Award from the Govt. of India and served as a Ramanujan Fellow at the Indian Institute of Technology, Indore.

Dr. Somasekharan’s laboratory is located at the Vancouver Prostate Centre and focuses on RNA biology. The laboratory is particularly interested in interdisciplinary research to understand the molecular mechanism of regulation of RNA in health and disease. Current research programs in the Somasekharan laboratory include:
(1) the relationship between RNA granule machinery and prostate cancer treatment resistance,
(2) the role of epitranscriptomic (m6A) RNA modifications in the translational regulation of androgen receptor (AR) mRNA,
(3) the mechanism of liquid-liquid phase separation (LLPS) of intrinsically disordered proteins - G3BP1, FMRP and YTHDF3- and RNA,
(4) molecular mechanisms of the control of gene expression at multiple levels - mRNA synthesis, transport, localisation and degradation, and
(5) multiomics approach to profile RNA granules and define selective mRNA translation.

Click here for Dr. Somasekharan’s publication list.  


Updated January 10, 2022

A World Class Centre

The Vancouver Prostate Centre (VPC) has a track record of success that has earned it a reputation as one of the world’s most respected cancer facilities. It is a National Centre of Excellence and a designated Centre of Excellence for Commercialization and Research.


Pars for Prostate fundraiser: September 22, 2022

The First Annual Pars for Prostate golf fundraiser in support of Prostate Cancer Foundation BC takes place September 22, 2022 at Westwood Plateau Golf Course. For information and to register please visit www.parsforprostate.ca

Dr. Black

Terry Fox Run fundraiser: September 18th, 2022

The 42nd Annual Terry Fox Run is taking place on Sunday September 18, 2022. If you are able, please consider joining and/or donating to our team (tax receipts issued), raising funds for the Terry Fox Foundation's ground-breaking cancer research


Work at the Vancouver Prostate Centre

Tuesday, September 20, 2022

Dr Mads Daugaard develops an AI cell analytics app which could supercharge biotechnology research

Wednesday, July 20, 2022

With just a tablespoon of blood, B.C. researchers aim to transform cancer treatment