Current Employment Opportunities

Critical funding from our research partners and donors has helped us to attract and retain the very best research talent from around the world, which in turn, increases our ability to move discoveries further along into clinical research and eventually treatments.

 

Date Posted: 
Thursday, June 25, 2020

Postdoctoral Fellow in Computational Chemistry (Machine Learning/COVID-19 Drug Discovery), Cherkasov Lab

The Vancouver Prostate Centre (VPC) has an exceptional opportunity available for a Postdoctoral Research Fellow in Computational Chemistry (Machine Learning/COVID-19 Drug Discovery to join Dr. Artem Cherkasov's research team.


The Vancouver Prostate Centre
VPC has a large, multi-disciplinary research program that undertakes basic, clinic, and translational research. It is a National Centre of Excellence and a designated Centre of Excellence for Commercialization and Research. It is affiliated with the University of British Columbia and the Vancouver Coastal Health Authority.

Cherkasov Lab
Professor Artem Cherkasov is looking for a talented Postdoctoral Research Fellow with a demonstrated research background in machine learning to join his computer-aided drug design group. The Postdoctoral Fellow will work on exciting drug discovery programs providing cutting-edge deep learning docking strategy --"Deep Docking"--to support structure-based and ligand-based virtual screening and lead optimization for SARS-COV-2 antivirals. Dr. Cherkasov (Professor, University of British Columbia) has recently been awarded four COVID-19 Rapid Response Grants and is collaborating with advanced computing companies to deploy machine learning to virtually screen 50B+ compounds for multiple COVID-19 therapeutic targets.

More information on Dr. Cherkasov and his team can be found here: www.prostatecentre.com/about-us/people/dr-art-cherkasov.

Qualifications and Requirements

  • PhD in Computational Chemistry or Computational Biochemistry.
  • Excellent problem solving and communication skills.
  • Research experience in developing machine learning methods for life science.
  • Strong Deep-learning programming experience with GPUs.
  • Statistical data analysis and database management skills.
  • Demonstrated experience using various programming languages including Python, BASH, Perl, AWK, and SVL.
  • Well-developed portfolio of open-source software available on GitHub
  • Solid background in computational chemistry, biological chemistry, organic chemistry, medicinal chemistry and pharmacokinetics.
  • Practical experience in structure-based and ligand-based drug design and compound library design.
  • Familiarity with state-of-the-art modeling and cheminformatics tools such as Molecular Operating Environment (MOE), Schrödinger, and OpenEye suite of programs.

Duties

  • Work with Dr. Cherkasov and collaborators to develop and/or apply cutting-edge computational approaches--Deep Docking--to screen 50B+ compounds for multiple SARS-CoV-2 viral targets.
  • Reading published papers and adapting procedures accordingly.
  • Liaising with collaborators and presenting research findings at international conferences.
  • Preparing manuscripts for submission to high impact journals.
  • Assisting with the creation of research proposals to be submitted to granting agencies.

Application Procedures
To apply for this position, please email careersatprostatecentre [dot] com with subject line Postdoctoral Research Fellow, Cherkasov Lab with the following items attached:

  • Current CV
  • Cover letter

NOTE: No telephone calls or drop-in inquiries accepted. Only those under consideration will be contacted.

Date Posted: 
Monday, January 18, 2021

Postdoctoral Fellow, Zoubeidi Lab

The Vancouver Prostate Centre (VPC) has an exceptional opportunity available for a Postdoctoral Research Fellow, Zoubeidi Lab to join our research team.

The Vancouver Prostate Centre
The VPC has a large number of multi-disciplinary research programs in basic, clinic, and translational cancer research. It is a National Centre of Excellence and a designated Centre of Excellence for Commercialization and Research. It is affiliated with the University of British Columbia and the Vancouver Coastal Health Authority.

Zoubeidi Lab
Dr. Amina Zoubeidi’s lab is focused on deciphering mechanisms of prostate cancer treatment resistance, with a particular emphasis on transcriptional and epigenetic plasticity. The lab is currently seeking applications for a talented, hard-working, independent, and highly motivated individual to join as a Postdoctoral fellow. The successful candidate will have the opportunity to study the interplay between epigenomics and transcriptional regulation in cell plasticity and emergent treatment-resistant prostate cancer.  She/he will utilize multi-omic profiling techniques (including, ChIP-seq, ATAC-seq, and RNA-seq), which will be complemented by functional studies of gene function in vitro and in vivo.

More information on Dr. Zoubeidi and her team can be found here: https://www.prostatecentre.com/about-us/people/dr-amina-zoubeidi

Qualifications and Requirements

  • PhD in Biochemistry, Molecular Biology, or similar.
  • Demonstrated experience in genetic and epigenetic profiling techniques is required.
  • Proven ability to work both independently and in a team environment.
  • Strong problem-solving skills.
  • Excellent written and verbal communication skills.
  • Computation experience is considered an asset, but is not required for this position.

Application Procedures
To apply for this position, please email careersatprostatecentre [dot] com with subject line Postdoctoral Research Fellow, Zoubeidi Lab with the following items attached:

  • Current CV
  • cover letter

Closing Date: We will commence reviewing applications on February 28, 2021. We thank all applicants for their interest. However, due to the high volume of applications received, only shortlisted candidates will be contacted. No phone calls or drop-in inquiries please.

Date Posted: 
Friday, January 22, 2021

Laboratory Research Assistant, Daugaard Lab

The Vancouver Prostate Centre (VPC) has an exceptional opportunity available for several regular, fulltime Laboratory Research Assistants to join Dr. Mads Daugaards’ research team.

The Vancouver Prostate Centre
VPC has a large, multi-disciplinary research program that undertakes basic, clinic, and translational research. It is a National Centre of Excellence and a designated Centre of Excellence for Commercialization and Research. It is affiliated with the University of British Columbia and the Vancouver Coastal Health Authority.

Daugaard Lab
The Daugaard laboratory focuses on innovative research in molecular cancer biology developing biotechnology for diagnostic and therapeutic use in different cancer indications. The successful applicants will work in a multi-disciplinary research team with access to state-of-the-art equipment and facilities in collaboration with national and international research groups and biotech companies. More information on Dr. Daugaard and his team can be found here: http://www.prostatecentre.com/about-us/people/dr-mads-daugaard.

Project description
The successful applicants will be part of a new program that aims to characterize and provide development support for three novel first-in-class DNA repair inhibitors. The research program is part of a collaboration between the Daugaard Lab and the biotech industry that will support IND-enabling of novel DNA repair antagonists for clinical trials within 2-3 years. The successful applicants will be an integrated part of a translational bench-to-bedside program that operates across the academia-industry spaces.

Responsibilities
The successful applicants will be working in a team structure with research trainees and project managers. Key aspects of the job include performing i) human cell culture work; ii) small-molecule in vitro screening and validation; iii) in vitro functional assay-development and optimization; iv) kinetics assays (e.g., IC50 analyses); v) in vivo models of human cancers. Responsibilities include:

  • Follow tutorial documents, procedures, methods and study protocols to provide a proficient level of support for in vivo studies.
  • Work in vitro with human cell lines and small-molecule compounds.
  • Implement data management and documentation practices.
  • Collaborate with management, peers and research partners to support in vitro and/or in vivo studies.

Qualifications and Experience

  • BA or higher in biochemistry, biology, biomedical engineering, molecular biology or similar field.
  • Minimum two years relevant work experience including working with small-molecules in vitro plus in vivo tumor models.
  • Familiarity with PARP inhibitors will be beneficial.
  • Proficiency with in vivo methods (e.g., dosing, sample collection, monitoring) and lab procedures.
  • Effective communication skills (both written and verbal) and a communication style that contributes to a collaborative work environment.
  • Strong problem-solving skills.
  • Organized and detailed orientated, with ability to meet timelines/deliverables/milestones.
  • Demonstrated ability to establish effective work relationships and participate in a team culture.
  • Flexibility - willing and able to work occasional weekends and statutory holidays.

Compensation
Salary range for this position is $48,834 to $75,853 per annum and we anticipate a starting salary in the $50,000 to $60,000 per annum range depending on work experience and skillset.

Application Procedures
To join our team, please email careersatprostatecentre [dot] com with subject line Laboratory Research Assistant, Daugaard Lab with the following items attached:

  • Cover letter
  • Resume

Closing Date: We will commence reviewing applications as of February 1, 2021 and our preferred start date is March 1, 2021.

Note: We thank all applicants for their interest. However, due to the high volume of applications received, only shortlisted candidates will be contacted. No phone calls please.

Date Posted: 
Tuesday, March 16, 2021

Clinical Trials Coordinator (temporary, full time)

The Vancouver Prostate Centre (VPC) has an exceptional opportunity available for a temporary, fulltime Clinical Trials Coordinator.

The Vancouver Prostate Centre
VPC has a large, multi-disciplinary research program that undertakes basic, clinic, and translational research. It is a National Centre of Excellence and a designated Centre of Excellence for Commercialization and Research. It is affiliated with the University of British Columbia and the Vancouver Coastal Health Authority.

Clinical Trials Coordinator
Handles all aspects of enrollment and follow-up of clinical research study patients including initial recruitment of study subjects, continued follow up with enrolled subjects, and collection and maintenance of clinical research related data.

Responsibilities
Coordinate Phase I-IV clinical trials; process regulatory documentation; complete case report forms; resolve data queries; recruit/screen patients according to protocol; schedule patient study visits and tests; process and ship study specimens; coordinate sponsor visits; participate in audits; assist with processing safety reports; and attend investigator initiation meetings. Key duties include:

  • Manage recruitment, screening, enrollment and data collection of study participants, ensuring protocol compliance.
  • Coordinate and manage patient study visits and tests.
  • Responsible for data and source documentation, as well as adverse event reporting.
  • Process and ship study specimens.
  • Schedule and conduct study initiation, monitoring and close-out visits with sponsors, Contract Research Organizations and other applicable parties.
  • Participate in the conduct of audits by study sponsors, Contract Research Organizations, Health Canada and Food and Drug Administration and other entities as required.

Qualifications and Experience

  • Grade 12 plus additional relevant training such as a Medical Office Assistant certificate/diploma.
  • Three years of related professional experience such as coordinating clinical trials.
  • Knowledge of relevant regulatory and ethical guidelines and principles for conducting research with human subjects.
  • Laboratory experience or willing to train on protocols to process blood and urine samples.
  • Phlebotomy experience or willing to train on Phlebotomy.
  • Experience with case report form creation and completion.
  • Experience with electronic data capture platforms and ability to resolve data queries.
  • Excellent organization and communication skills with ability to effectively communicate and provide support to investigators and patients.
  • Demonstrated meticulous attention to detail
  • Solid computer expertise.
  • Able to work independently and as part of a team, with minimal supervision.
  • Proven decision-making and effective time management.

Application Procedures
To join our team, please email careersatprostatecentre [dot] com with subject line Clinical Trials Coordinator with the following items attached:

  • Cover letter
  • Resume

Closing Date: Review of applications will begin March 29, 2021 and ideal start date will be as soon as possible.

Note: We thank all applicants for their interest. However, due to the high volume of applications received, only shortlisted candidates will be contacted. No phone calls please.

A World Class Centre

The Vancouver Prostate Centre (VPC) has a track record of success that has earned it a reputation as one of the world’s most respected cancer facilities. It is a National Centre of Excellence and a designated Centre of Excellence for Commercialization and Research.

Events

VPC Terry Fox team 2016

Terry Fox Run - September 20, 2020

The 40th annual Terry Fox Run takes place on Sunday September 20 across Canada, as a virtual event.  Please consider donating to or joining our TFRI-VPC team as we raise funds to enable The Terry Fox Foundation & The Terry Fox Research Institute to continue their support of innovative and progressive cancer research programs

Employment

Work at the Vancouver Prostate Centre

Thursday, March 4, 2021

Dr. Collins awarded CIHR Project Grant

Dr. Colin Collins
Friday, January 22, 2021

Dr. Nappi receives MSFHR 2020 Health Professional-Investigator Award