Current Employment Opportunities

Critical funding from our research partners and donors has helped us to attract and retain the very best research talent from around the world, which in turn, increases our ability to move discoveries further along into clinical research and eventually treatments.

 

Date Posted: 
Tuesday, June 23, 2020

Postdoctoral Fellow, Dong Lab

The Vancouver Prostate Centre (VPC) has an exceptional opportunity available for a Postdoctoral Fellow, Dong Lab to join our research team.

The VPC has a large number of multi-disciplinary research programs in basic, clinic, and translational cancer research. It is a National Centre of Excellence and a designated Centre of Excellence for Commercialization and Research. It is affiliated with the University of British Columbia and the Vancouver Coastal Health Authority.

Dong Lab
The Postdoctoral Fellow will work under the supervision of Dr. Xuesen Dong, within a world-class multi-disciplinary team. Our research focuses on the mechanisms of therapy-resistant prostate cancers and the development of therapeutics to manage the disease (representative publications PMID: 32634132, 30910347, 27180064, 31819165). Ongoing projects include: 1) deciphering cancer stem cell signal pathways in regulating neuroendocrine prostate cancers and 2) circular RNA as diagnostic biomarkers of prostate cancers.

We are looking for multiple candidates to expand the existing projects aimed at understanding how Lin28 regulates stem cell network to counteract therapy-induced stress, and applying computer-aided drug design to develop Lin28 inhibitors. Candidates with a circular RNA research background are also welcome to join us.

Post-doctoral fellows will have opportunities to lead independent research projects, develop inter- and intra-laboratory collaborations, and publish in scientific journals. The successful candidates will have the opportunity to tackle cutting edge-problems in prostate cancer research, interact with world class scientists, and gain experiences and develop skillsets for his/her next career stage.

More information on Dr. Dong and his team can be found here: www.prostatecentre.com/about-us/people/dr-xuesen-dong.

Qualifications and Requirements

  • Relevant PhD degree in Molecular Biology, Biochemistry or Cell Biology.
  • Minimum five years related laboratory experience.
  • Demonstrated expertise with cell culture/transfection, western blotting, real time PCR and molecular cloning.
  • Experience with lenti-virus manipulation and animal work will be considered an asset.
  • Strong problem-solving skills.
  • Statistical data analysis and database management skills.
  • Excellent written/verbal communication skills and organizational skills
  • Demonstrated ability to work in a team environment.

Application Procedures
To apply for this position, please email careersatprostatecentre [dot] com with subject line Post-doctoral Research Fellow, Dong Lab with the following items attached:

  • Current CV
  • Cover letter

NOTE: Applications will be accepted until a qualified candidate is found. No telephone calls or drop-in inquiries accepted. Only those under consideration will be contacted.

Listing updated August 12, 2020

Date Posted: 
Thursday, June 25, 2020

Postdoctoral Fellow in Computational Chemistry (Machine Learning/COVID-19 Drug Discovery), Cherkasov Lab

The Vancouver Prostate Centre (VPC) has an exceptional opportunity available for a Postdoctoral Research Fellow in Computational Chemistry (Machine Learning/COVID-19 Drug Discovery to join Dr. Artem Cherkasov's research team.


The Vancouver Prostate Centre
VPC has a large, multi-disciplinary research program that undertakes basic, clinic, and translational research. It is a National Centre of Excellence and a designated Centre of Excellence for Commercialization and Research. It is affiliated with the University of British Columbia and the Vancouver Coastal Health Authority.

Cherkasov Lab
Professor Artem Cherkasov is looking for a talented Postdoctoral Research Fellow with a demonstrated research background in machine learning to join his computer-aided drug design group. The Postdoctoral Fellow will work on exciting drug discovery programs providing cutting-edge deep learning docking strategy --"Deep Docking"--to support structure-based and ligand-based virtual screening and lead optimization for SARS-COV-2 antivirals. Dr. Cherkasov (Professor, University of British Columbia) has recently been awarded four COVID-19 Rapid Response Grants and is collaborating with advanced computing companies to deploy machine learning to virtually screen 50B+ compounds for multiple COVID-19 therapeutic targets.

More information on Dr. Cherkasov and his team can be found here: www.prostatecentre.com/about-us/people/dr-art-cherkasov.

Qualifications and Requirements

  • PhD in Computational Chemistry or Computational Biochemistry.
  • Excellent problem solving and communication skills.
  • Research experience in developing machine learning methods for life science.
  • Strong Deep-learning programming experience with GPUs.
  • Statistical data analysis and database management skills.
  • Demonstrated experience using various programming languages including Python, BASH, Perl, AWK, and SVL.
  • Well-developed portfolio of open-source software available on GitHub
  • Solid background in computational chemistry, biological chemistry, organic chemistry, medicinal chemistry and pharmacokinetics.
  • Practical experience in structure-based and ligand-based drug design and compound library design.
  • Familiarity with state-of-the-art modeling and cheminformatics tools such as Molecular Operating Environment (MOE), Schrödinger, and OpenEye suite of programs.

Duties

  • Work with Dr. Cherkasov and collaborators to develop and/or apply cutting-edge computational approaches--Deep Docking--to screen 50B+ compounds for multiple SARS-CoV-2 viral targets.
  • Reading published papers and adapting procedures accordingly.
  • Liaising with collaborators and presenting research findings at international conferences.
  • Preparing manuscripts for submission to high impact journals.
  • Assisting with the creation of research proposals to be submitted to granting agencies.

Application Procedures
To apply for this position, please email careersatprostatecentre [dot] com with subject line Postdoctoral Research Fellow, Cherkasov Lab with the following items attached:

  • Current CV
  • Cover letter

NOTE: No telephone calls or drop-in inquiries accepted. Only those under consideration will be contacted.

A World Class Centre

The Vancouver Prostate Centre (VPC) has a track record of success that has earned it a reputation as one of the world’s most respected cancer facilities. It is a National Centre of Excellence and a designated Centre of Excellence for Commercialization and Research.

Events

VPC Terry Fox team 2016

Terry Fox Run - September 20, 2020

The 40th annual Terry Fox Run takes place on Sunday September 20 across Canada, as a virtual event.  Please consider donating to or joining our TFRI-VPC team as we raise funds to enable The Terry Fox Foundation & The Terry Fox Research Institute to continue their support of innovative and progressive cancer research programs

Employment

Work at the Vancouver Prostate Centre

Thursday, September 24, 2020

Drs. Gleave, Lack and Wang awarded CIHR Project Grants

Tuesday, September 8, 2020

MSFHR 2020 Awardees: Drs. Hach, Gentile, Massah

Thursday, June 25, 2020

Drs. Cherkasov and Jean receive CIHR grant to find new antiviral drugs to treat COVID-19